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Diethyl-pythiDC
DC12140  (CAS:1821370-70-0)
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100mg USD 950 in stock
250mg USD 1900 in stock
1g USD 3800 in stock
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Fields of Application :
Diethyl-pythiDC is an inhibitor of collagen prolyl 4-hydroxylases (CP4Hs).
CAS Number: 1821370-70-0
Purity:

Molecular Weight: 306.34
Molecular Formula: C14H14N2O4S
Quality Control: HPLCNMR LC/MS(Please contact us to get the QC report)
Synonyms:
Chemical Name:
Storage: 2 years -20C Powder, 2 weeks4C in DMSO,6 months-80C in DMSO
Note: Products for research use only, not for human use
Description:
In Vitro Diethyl-pythiDC inhibits CP4H activity in cultured cells at concentrations that do not cause iron deficiency. MDA-MB-231 cells are treated with biheteroaryl dicarboxylates, and assayed for cytotoxicity and indicators of iron deficiency. None of the esterified biheteroaryl dicarboxylates exhibited cytotoxic activity at high micromolar concentrations. Cells treated with dihydroxybenzoate (EDHB demonstrate a strong iron-deficient phenotype. In contrast, cells treated with Diethyl-pythiDC (Diethyl pythiDC) appear to be normal at concentrations as high as 500 M. Treatment with Diethyl-pythiDC and low levels of diethyl pyimDC does not affect the level of TfR, HIF-1, or ferritin.
References:
O=C(C1=CC=C(C2=NC=C(C(OCC)=O)S2)N=C1)OCC
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