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RSV-IN-1
DC12132  (CAS:861139-16-4)
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Fields of Application :
RSV-IN-1 is a human respiratory syncytical virus (hRSV) inhibitor, with an IC50 of 0.11 M.
CAS Number: 861139-16-4
Purity:

Molecular Weight: 427.48
Molecular Formula: C20H21N5O4S
Quality Control: HPLCNMR LC/MS(Please contact us to get the QC report)
Synonyms:
Chemical Name:
Storage: 2 years -20C Powder, 2 weeks4C in DMSO,6 months-80C in DMSO
Note: Products for research use only, not for human use
Description:
In Vitro The concentration of P13 that reduces the number of RSV plaques in HEp-2 cells by 50% (IC50) is 0.11 M. The concentration of P13 that reduces the viability of HEp-2 by 50% (CC50) is 310 M. Note that some cytotoxicity of P13 observed at 500 M might be due to DMSO solvent. Hence, the selective index (CC50/IC50) values is 2818 for P13. Note that even at the relatively high concentrations P13 does not completely block the development of RSV plaques. These escape plaques are of smaller size and of non-syncytial phenotype as compared to plaques formed in the absence of inhibitor.
References:
O=S(C1=CC=C(OC)C(C2=NN=C3N2N=C(C)C4=C3C=CC=C4)=C1)(N(CCO)C)=O
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