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CNT2 inhibitor-1
DC12103  (CAS:880155-70-4)
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Fields of Application :
CNT2 inhibitor-1 is a potent concentrative nucleoside transporter 2 Inhibitor (CNT2), with an IC50 of 640 nM for hCNT2.
CAS Number: 880155-70-4
Purity:

Molecular Weight: 448.47
Molecular Formula: C23H24N6O4
Quality Control: HPLCNMR LC/MS(Please contact us to get the QC report)
Synonyms:
Chemical Name:
Storage: 2 years -20C Powder, 2 weeks4C in DMSO,6 months-80C in DMSO
Note: Products for research use only, not for human use
Description:
In Vitro CNT2 inhibitor-1 (compound 48) exhibits 81-fold more potent inhibitory activity than the parent compound 12. In addition, CNT2 inhibitor-1 exhibits inhibitory activity 1500-fold more potent than that of 2-deoxy-5-fluorouridine, phlorizin, and 7,8,3-trihydroxyflavone, which are well-known hCNT2 inhibitors. CNT2 inhibitor-1 (compound 1) is a potent inhibitor with poor solubility.
References:
OC[C@@H]1[C@H]([C@H]([C@H](N2C(NCC3=CC=C(C4=CC=CC=C4)C=C3)=NC5=C2N=CN=C5N)O1)O)O
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