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CHIR-99021 (CT99021)
DC1023  (CAS:252917-06-9)
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Fields of Application :
CHIR-99021 is a glycogen synthase kinase 3 beta inhibitor that has antiproliferative activity in vitro and in vivo.
CAS Number: 252917-06-9
Purity:

99%

Molecular Weight: 465.34
Molecular Formula: C22H18Cl2N8
Quality Control: HPLCNMR LC/MS(Please contact us to get the QC report)
Synonyms: CHIR 99021, CT 99021,CHIR99021,CT-99021
Chemical Name: 6-(2-(4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-ylamino)ethylamino)nicotinonitrile hydrochloride
Storage: 2 years -20C Powder, 2 weeks4C in DMSO,6 months-80C in DMSO
Note: Products for research use only, not for human use
Description:
CHIR-99021 (CT99021) is a glycogen synthase kinase 3 (GSK3) inhibitor that has antiproliferative activity in vitro and in vivo. CHIR-99021 inhibits GSK-3 with IC50 at 7 nM. In a series of carcinoma cell lines, the IC50 of CHIR99021 For proliferation is about 10M. For the detailed information about the solubility of CHIR-99021 (CT99021) in water, the solubility of CHIR-99021 (CT99021) in DMSO, the solubility of CHIR-99021 (CT99021) in PBS buffer, the animal experimenttest of CHIR-99021 (CT99021),the in vivo,in vitro and clinical trial test of CHIR-99021 (CT99021),the cell experimenttest of CHIR-99021 (CT99021),the IC50, EC50 and Affinity of CHIR-99021 (CT99021), please contact DC Chemicals.
References:
CC1=CN=C(N1)C2=CN=C(N=C2C3=C(C=C(C=C3)Cl)Cl)NCCNC4=NC=C(C=C4)C#N
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