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CTN06
DC22066  (CAS:)
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Fields of Application :
CTN06 is a potent Etk (BMX) and Btk dual inhibitor with IC50 of 200 and 50 nM, respectively.
CAS Number:
Purity:

Molecular Weight: 563.706
Molecular Formula: C33H37N7O2
Quality Control: HPLCNMR LC/MS(Please contact us to get the QC report)
Synonyms: CTN06|CTN 06
Chemical Name: N-(7-isobutyl-6-oxo-1-(3-(piperidin-1-yl)propyl)-5,6-dihydro-1H-imidazo[4,5-g]quinoxalin-2-yl)-4-(pyridin-4-yl)benzamide
Storage: 2 years -20C Powder, 2 weeks4C in DMSO,6 months-80C in DMSO
Note: Products for research use only, not for human use
Description:
CTN06 is a potent Etk (BMX) and Btk dual inhibitor with IC50 of 200 and 50 nM, respectively; weakly inhibits Itk (IC50=0.5 uM), and shows no inhibition on Src (IC50=5?uM) and Mer (IC50=10?uM); effectively kills PC3 and other prostate cancer cells, induces autophagy as well as apoptosis in prostate cancer cells; inhibits the phosphorylation of Btk, Etk and the downstream signal PLC2, Stat3, Akt in prostate cancer cells; inhibits PC3 xenograft tumor growth in vivo.
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