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DB818
DC22069  (CAS:790241-43-9)
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Fields of Application :
DB818 (DB-818, DB 818) is a small molecule inhibitor of HOXA9/DNA interaction through binding as minor groove DNA ligand on the HOXA9 cognate sequence.
CAS Number: 790241-43-9
Purity:

Molecular Weight: 360.439
Molecular Formula: C19H16N6S
Quality Control: HPLCNMR LC/MS(Please contact us to get the QC report)
Synonyms: DB818|DB-818;DB 818
Chemical Name: 2-(5-(4-carbamimidoylphenyl)thiophen-2-yl)-1H-benzo[d]imidazole-6-carboximidamide
Storage: 2 years -20C Powder, 2 weeks4C in DMSO,6 months-80C in DMSO
Note: Products for research use only, not for human use
Description:
DB818 (DB-818, DB 818) is a small molecule inhibitor of HOXA9/DNA interaction through binding as minor groove DNA ligand on the HOXA9 cognate sequence; directly bind to HOXA9-cognate sequence with Kd value of 4.6 nM (HBS sequence); alters HOXA9-mediated transcription, cell survival and cell cycle inHOXA9-mediated HOXA9-expressing murine MigA9 cell line.
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