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DS42450411
DC22079  (CAS:)
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Fields of Application :
DS42450411 (DS 42450411, DS-42450411) is a potent, orally active hepcidin production inhibitor with IC50 of 32 nM.
CAS Number:
Purity:

Molecular Weight: 348.494
Molecular Formula: C22H28N4
Quality Control: HPLCNMR LC/MS(Please contact us to get the QC report)
Synonyms: DS42450411|DS 42450411;DS-42450411
Chemical Name: 8-{1-[(1R,4R)-4-aminocyclohexyl]ethenyl}-5,5-dimethyl-5,6-dihydrobenzo[h]quinazolin-4-amine
Storage: 2 years -20C Powder, 2 weeks4C in DMSO,6 months-80C in DMSO
Note: Products for research use only, not for human use
Description:
DS42450411 (DS 42450411, DS-42450411) is a potent, orally active hepcidin production inhibitor with IC50 of 32 nM; The inhibition of hepcidin production of DS42450411 was suggested to be through the inhibition of DYRK1a or a kinase belonging to CMGC family; shows serum hepcidin-lowering effects in a mouse model of interleukin-6-induced acute inflammation.
References:
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