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RTS-V5
DC22084  (CAS:)
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RTS-V5 (Dual HDAC-proteasome inhibitor RTS-V5) is the first-in-class, dual HDAC-proteasome inhibitor with IC50 of 0.27 uM (HDAC6), inhibits HDAC8 (IC50=0.53 uM), and low activity against HDAC/1/2/3.
CAS Number:
Purity:

Molecular Weight: 525.606
Molecular Formula: C27H35N5O6
Quality Control: HPLCNMR LC/MS(Please contact us to get the QC report)
Synonyms: RTS-V5|Dual HDAC-proteasome inhibitor RTS-V5
Chemical Name: N1-((S)-1-(((S)-1-(Benzylamino)-1-oxopropan-2-yl)amino)-4-(neopentylamino)-1,4- dioxobutan-2-yl)-N4 -hydroxyterephthalamide
Storage: 2 years -20C Powder, 2 weeks4C in DMSO,6 months-80C in DMSO
Note: Products for research use only, not for human use
Description:
RTS-V5 (Dual HDAC-proteasome inhibitor RTS-V5) is the first-in-class, dual HDAC-proteasome inhibitor with IC50 of 0.27 uM (HDAC6), inhibits HDAC8 (IC50=0.53 uM), and low activity against HDAC/1/2/3; demonstrates cytotoxicity against leukemia and multiple myeloma cell lines as well as therapy-refractory primary patient-derived leukemia cells.
References:
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