LOGIN IN
REGISTER
PRODUCTS
More than 5000 active chemicals with high quality for research!

Email sales@dcchemicals.com

        order@dcchemicals.com

        info@dcchemicals.com


Phone:  +86-21-58447131

Fax   +86-21-61642470

HS-1371
DC12045  (CAS:2158197-70-5)
(Based on popularity)
Size Price Availability
100mg USD 700 in stock
250mg USD 1200 in stock
1g USD 2400 in stock
We match the best price and quality on market.
 
 
Email: order@dcchemicals.com
Tel: +86-21-58447131
Fax:+86-21-61642470
Fields of Application :
HS-1371 is a novel kinase inhibitor of RIP3-mediated necroptosis.
CAS Number: 2158197-70-5
Purity:

>98%

Molecular Weight: 384.195
Molecular Formula: C24H24N4O
Quality Control: HPLCNMR LC/MS(Please contact us to get the QC report)
Synonyms: HS-1371; HS 1371; HS1371,2158197-70-5
Chemical Name: 7-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)-4-(p-tolyloxy)quinoline
Storage: 2 years -20C Powder, 2 weeks4C in DMSO,6 months-80C in DMSO
Note: Products for research use only, not for human use
Description:
HS-1371 inhibited TNF-induced necroptosis but did not inhibit TNF-induced apoptosis, indicating that this novel inhibitor has a specific inhibitory effect on RIP3-mediated necroptosis via suppression of RIP3 kinase activity.The results suggest that HS-1371 could serve as a potential preventive or therapeutic agent for RIP3 hyperactivation-mediated diseases.
References:
CC1=CC=C(OC2=CC=NC3=CC(C4=CN(C5CCNCC5)N=C4)=CC=C23)C=C1
About us Products Services ordering sitemap
Phone: +86-21-58447131Fax: +86-21-61642470
ADDRoom 610, Building 15, Jinxiang Rd 201, Pudong,Shanghai, China
CopyRight-2010-2013 DC Chemicals All Rights Reserved