Lefamulin(BC-3781)

Cat. No.: DC8172 Featured
Lefamulin(BC-3781)
Chemical Structure
1061337-51-6
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Field of application
Lefamulin is a semi-synthetic compound that inhibits the synthesis of bacterial protein, which is required for bacteria to grow.
Cas No.: 1061337-51-6
Chemical Name: (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propano-3aH-cyclopenta[8]annulen-8-yl {[(1R,2R,4R)-4-amino-2-hydroxycyclohexyl]sulfanyl}acetate
Synonyms: BC-3781,BC 3781,BC3781
SMILES: O=C(O[C@H]1[C@@]([C@H](C)CC2)(C)[C@@](C(CC3)=O)([H])[C@]32[C@@H](C)[C@H](O)[C@](C)(C=C)C1)CS[C@H]4[C@H](O)C[C@H](N)CC4
Formula: C28H45NO5S
M.Wt: 507.3
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Lefamulin is a semi-synthetic compound that inhibits the synthesis of bacterial protein, which is required for bacteria to grow. Lefamulin acts by binding to the peptidyl transferase center, or PTC, on the bacterial ribosome in such a way that it interferes with the interaction of protein production at two key sites known as the “A” site and the “P” site, resulting in the inhibition of bacterial proteins and the cessation of bacterial growth. Lefamulin’s binding occurs with high affinity, high specificity and at molecular sites that are different than other antibiotic classes. For the detailed information of Lefamulin(BC-3781), the solubility of Lefamulin(BC-3781) in water, the solubility of Lefamulin(BC-3781) in DMSO, the solubility of Lefamulin(BC-3781) in PBS buffer, the animal experiment (test) of Lefamulin(BC-3781), the cell expriment (test) of Lefamulin(BC-3781), the in vivo, in vitro and clinical trial test of Lefamulin(BC-3781), the EC50, IC50,and affinity,of Lefamulin(BC-3781), For the detailed information of Lefamulin(BC-3781), the solubility of Lefamulin(BC-3781) in water, the solubility of Lefamulin(BC-3781) in DMSO, the solubility of Lefamulin(BC-3781) in PBS buffer, the animal experiment (test) of Lefamulin(BC-3781), the cell expriment (test) of Lefamulin(BC-3781), the in vivo, in vitro and clinical trial test of Lefamulin(BC-3781), the EC50, IC50,and affinity,of Lefamulin(BC-3781), Please contact DC Chemicals.
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MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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