PF-06409577

  Cat. No.:  DC11466   Featured
PF-06409577
Chemical Structure
1467057-23-3
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More than 5000 active chemicals with high quality for research!
Field of application
PF-06409577 is a potent and selective allosteric activator of AMPK α1β1γ1 isoform with an EC50 of 7 nM.
Cas No.: 1467057-23-3
Chemical Name:
Synonyms: PF-06409577,PF 06409577,PF06409577
SMILES: O=C(C1=CNC2=C1C=C(C3=CC=C(C4(O)CCC4)C=C3)C(Cl)=C2)O
Formula: C19H16ClNO3
M.Wt: 341.79
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication:
Description:
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In Vitro:
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Kinase Assay:
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MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC11466 PF-06409577 PF-06409577 is a potent and selective allosteric activator of AMPK α1β1γ1 isoform with an EC50 of 7 nM.
DC12020 MK-8722 MK-8722 is a systemic, Direct Pan-Activator of AMP-Activated Protein Kinase.
DC8182 Bempedoic Acid(ETC-1002;ESP-55016) ETC-1002(ESP-55016) is a novel, first-in-class, orally available, once-daily LDL-C lowering small molecule; activator of hepatic AMP-activated protein kinase (AMPK); also has potent inhibitory activity against hepatic ATP-citrate lyase(IC50=29 uM).
DC7045 A-769662 A-769662 is a potent, reversible AMPK activator with EC50 of 0.8 μM, little effect on GPPase/FBPase activity.