Remdesivir(GS-5734)

  Cat. No.:  DC11735   Featured
Remdesivir(GS-5734)
Chemical Structure
1809249-37-3
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Field of application
Remdesivir is a novel RNA-dependent RNA Polymerase,(RdRp) inhibitor. The purity of remdesivir>99.8%,signal impurity<0.05%.
Cas No.: 1809249-37-3
Chemical Name: 2-ethylbutyl ((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[1,2-b]pyridazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
Synonyms: GS 5734;GS5734;Remdesivir
SMILES: C[C@@H](C(=O)OCC(CC)CC)N[P@](=O)(OC[C@@H]1[C@@H](O)[C@@H](O)[C@@](C2N3C(C(=NC=N3)N)=CC=2)(C#N)O1)OC1C=CC=CC=1
Formula: C27H35N6O8P
M.Wt: 602.57
Purity: >99.8%,signal impurity<0.05%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication:
Description: GS-5734 (Remdesivir) is a monophosphoramidate prodrug of adenosine analogue that exhibits antiviral activity against multiple variants of EBOV (EC50=70-140 nM) and other filoviruses (EC50=0.019-1.48 uM) in cell-based assays; suppresses EBOV replication and protects 100% of EBOV-infected animals against lethal disease, ameliorating clinical disease signs and pathophysiological markers.
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In Vitro:
References:
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC11735 Remdesivir(GS-5734) Remdesivir is a novel RNA-dependent RNA Polymerase,(RdRp) inhibitor. The purity of remdesivir>99.8%,signal impurity<0.05%.