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SB9200(Inarigivir soproxil)
DC10729  (CAS:942123-43-5)
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10mg USD 950 In stock
25mg USD 1700 In stock
50mg USD 2900 In stock
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Fields of Application :
SB9200(Inarigivir soproxil) is a novel agonist of innate immunity, shows potent antiviral activity against resistant HCV variants.
CAS Number: 942123-43-5
Purity:

>98%

Molecular Weight: 703.62
Molecular Formula: C25H34N7O13PS
Quality Control: HPLCNMR LC/MS(Please contact us to get the QC report)
Synonyms: SB9200,SB 9200,SB-9200
Chemical Name:
Storage: 2 years -20C Powder, 2 weeks4C in DMSO,6 months-80C in DMSO
Note: Products for research use only, not for human use
Description:
SB 9200 is a novel, first-in-class oral modulator of innate immunity that is believed to act via the activation of the RIG-I and NOD2 pathways. SB 9200 has broad-spectrum antiviral activity against RNA viruses including hepatitis C virus (HCV), norovirus, respiratory syncytial virus, and influenza and has demonstrated activity against hepatitis B virus (HBV) in vitro and in vivo. In phase I clinical trials in chronically infected HCV patients, SB 9200 has been shown to reduce HCV RNA by up to 1.9 log. SB 9200 is active against diverse HCV genotypes and is also effective against HCV derived from patients who relapse following direct-acting antiviral treatment, including viruses containing known NS5A resistance-associated sequences. These data confirm the broad antiviral activity of SB 9200 and indicate that it may have clinical utility in HCV patients who have failed to respond to current antiviral regimens.
References:
N1=C(N)C2N=CN([C@H]3O[C@@H](COP(O[C@@H]4[C@@H](CO)O[C@H](N5C(=O)NC(=O)C=C5)[C@H]4OC)(SCOC(OC(C)C)=O)=O)[C@H](O)C3)C=2N=C1
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