SB-203580

  Cat. No.:  DC1004   Featured
SB-203580
Chemical Structure
152121-47-6
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Field of application
SB203580 is a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM and blocks PKB phosphorylation with IC50 of 3-5 μM.
Cas No.: 152121-47-6
Chemical Name: 4-(4-(4-fluorophenyl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-5-yl)pyridine
Synonyms: SB203580,SB 203580
SMILES: CS(=O)C1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F
Formula: C21H16FN3Os
M.Wt: 377.43
Purity: 99%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication:
Description: For the detailed information about the solubility of SB-203580 in water, the solubility of SB-203580 in DMSO, the solubility of SB-203580 in PBS buffer, the animal experiment(test) of SB-203580,the in vivo,in vitro and clinical trial test of SB-203580,the cell experiment(test) of SB-203580,the IC50, EC50 and Affinity of SB-203580, please contact DC Chemicals.
In Vivo:
In Vitro:
References:
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC9300 TA-02 TA-02 induces cardiomyocyte differentiation from human embryonic stem cells following mesoderm induction. Potently inhibits p38α, CK1δ and CK1ε (IC50 values are 20, 32 and 32 nM respectively).
DC7946 SKF-86002 SKF-86002 is a potent inhibitor of p38 MAP kinase wit IC50 of 0.5-1 uM; inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50 = 1 μM).
DC1004 SB-203580 SB203580 is a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM and blocks PKB phosphorylation with IC50 of 3-5 μM.
DC2097 SB202190 SB 202190 is a pyridinyl imidazole that inhibits the p38 pathway.
DC7491 RWJ67657 RWJ67657 is a selective p38α and p38β inhibitor (IC50 values are 1 and 11 μM respectively) that displays no activity at p38γ, p38δ and a range of other kinases.
DC5095 PD169316 PD169316 is a potent and selective p38 MAP kinase inhibitor