SC1(Pluripotin)

  Cat. No.:  DC7599   Featured
SC1(Pluripotin)
Chemical Structure
839707-37-8
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More than 5000 active chemicals with high quality for research!
Field of application
SC1(Pluripotin) is a sustainer of mES self-renewal and ERK 1 inhibitor
Cas No.: 839707-37-8
Chemical Name: N-(3-(7-(1,3-dimethyl-1H-pyrazol-5-ylamino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide
Synonyms:
SMILES: CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)N3CC4=CN=C(N=C4N(C3=O)C)NC5=CC(=NN5C)C
Formula: C27H25F3N8O2
M.Wt: 550.5
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication:
Description: SC1 is a small molecule shown to sustain self-renewal of mouse embryonic stem (mES) cells. In order to maintain embryonic stem cells in an undifferentiated state, it is typically necessary to use a combination of feeder cells, leukemia inhibitor factor (LIF) and bone morphogenic protein (BMP); SC1 (Pluripotin) allows For stem cell propagation in the absence of these factors. The activity of SC1 is mediated by Ras signaling which promotes self-renewal, and inhibition of ERK blocks differentiation.For the detailed information of SC1 (Pluripotin), the solubility of SC1 (Pluripotin) in water, the solubility of SC1 (Pluripotin) in DMSO, the solubility of SC1 (Pluripotin) in PBS buffer, the animal experiment (test) of SC1 (Pluripotin), the cell expriment (test) of SC1 (Pluripotin), the in vivo, in vitro and clinical trial test of SC1 (Pluripotin), the EC50, IC50,and Affinity of SC1 (Pluripotin), Please contact DC Chemicals.
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In Vitro:
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Kinase Assay:
Cell Assay:
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MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
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