Cat. No.:  DC7599   Featured
Chemical Structure
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More than 5000 active chemicals with high quality for research!
Field of application
SC1(Pluripotin) is a sustainer of mES self-renewal and ERK 1 inhibitor
Cas No.: 839707-37-8
Chemical Name: N-(3-(7-(1,3-dimethyl-1H-pyrazol-5-ylamino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide
Formula: C27H25F3N8O2
M.Wt: 550.5
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: SC1 is a small molecule shown to sustain self-renewal of mouse embryonic stem (mES) cells. In order to maintain embryonic stem cells in an undifferentiated state, it is typically necessary to use a combination of feeder cells, leukemia inhibitor factor (LIF) and bone morphogenic protein (BMP); SC1 (Pluripotin) allows For stem cell propagation in the absence of these factors. The activity of SC1 is mediated by Ras signaling which promotes self-renewal, and inhibition of ERK blocks differentiation.For the detailed information of SC1 (Pluripotin), the solubility of SC1 (Pluripotin) in water, the solubility of SC1 (Pluripotin) in DMSO, the solubility of SC1 (Pluripotin) in PBS buffer, the animal experiment (test) of SC1 (Pluripotin), the cell expriment (test) of SC1 (Pluripotin), the in vivo, in vitro and clinical trial test of SC1 (Pluripotin), the EC50, IC50,and Affinity of SC1 (Pluripotin), Please contact DC Chemicals.
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Kinase Assay:
Cell Assay:
Animal Administration:
Cat. No. Product name Field of application
DC8239 SL 0101-1 SL 0101-1 is a selective inhibitor of p90 Rsk (ribosomal S6 kinase) (IC50 = 89 nM for Rsk-2).
DC7599 SC1(Pluripotin) SC1(Pluripotin) is a sustainer of mES self-renewal and ERK 1 inhibitor
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