SRT1720 HCl

  Cat. No.:  DC7300   Featured
SRT1720 HCl
Chemical Structure
For research use only. We do not sell to patients.
We match the best price and quality on market.
We are official vendor of:
  • 20
  • 19
  • 18
  • 17
  • 16
  • 15
  • 14
  • 12
  • 11
  • 10
  • 9
  • 8
  • 13
  • 6
  • 5
  • 4
  • 3
  • 2
  • 1
More than 5000 active chemicals with high quality for research!
Field of application
SRT1720 is a selective SIRT1 activator with EC50 of 0.16 μM, but is >230-fold less potent for SIRT2 and SIRT3.
Cas No.: 1001645-58-4
Chemical Name: N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)quinoxaline-2-carboxamidehydrochloride
Synonyms: SRT-1720; SRT 1720
Formula: C25H23N7Os.HCl
M.Wt: 506.02
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: SRT1720 is a selective SIRT1 activator with EC50 of 0.16 μM, but is >230-fold less potent For SIRT2 and SIRT3.For the detailed information of SRT1720, the solubility of SRT1720 in water, the solubility of SRT1720 in DMSO, the solubility of SRT1720 in PBS buffer, the animal experiment (test) of SRT1720, the cell expriment (test) of SRT1720, the in vivo, in vitro and clinical trial test of SRT1720, the EC50, IC50,and Affinity of SRT1720, Please contact DC Chemicals.
In Vivo:
In Vitro:
Kinase Assay:
Cell Assay:
Animal Administration:
Cat. No. Product name Field of application
DC7428 Inauhzin Inauhzin(INZ) is a novel small molecule that effectively reactivates p53 by inhibiting SIRT1 activity, promotes p53-dependent apoptosis of human cancer cells without causing apparently genotoxic stress(IC50=3 uM, in A549 cell).
DC7127 EX-527(Selisistat) EX 527 is a potent and selective SIRT1 inhibitor with IC50 of 38 nM, exhibits >200-fold selectivity against SIRT2 and SIRT3.
DC10076 Thiomyristoyl Thiomyristoyl is a potent and specific SIRT2 inhibitor with an IC50 of 28 nM.
DC7315 Tenovin-6 Tenovin-6 is the water soluble analog of Tenovin-1 and acts as a potent SIRT1 (IC50=21 uM) and SIRT2 (IC50= 10 uM) inhibitor as well as p53 activator.
DC1065 Tenovin-1 Tenovin-1 is a p53 activator and acts through inhibition of protein-deacetylating activities of SirT1 and SirT2.
DC8412 SRT2104 SRT2104 (GSK2245840) is a selective SIRT1 activator involved in the regulation of energy homeostasis. Phase 2.
DC7300 SRT1720 HCl SRT1720 is a selective SIRT1 activator with EC50 of 0.16 μM, but is >230-fold less potent for SIRT2 and SIRT3.
DC10002 Salermide Salermide is an inhibitor of SIRT1 and SIRT2, causing tumor-specific apoptotic cell death. In MOLT4 leukemia cells, salermide causes 90% apoptosis within 72 hours (IC50 ~ 20 μM) by reactivating proapototic genes that are repressed by SIRT1.
DC10658 OSS-128167(SIRT6-IN-1) OSS-128167 is a novel SIRT6 inhibitor.
DC10579 CAY 10602 CAY10602 is a SIRT1 activator.