Verubecestat (MK-8931)

  Cat. No.:  DC9901   Featured
Verubecestat (MK-8931)
Chemical Structure
1286770-55-5
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Field of application
MK-8931 is a BACE1 inhibitor. MK-8931 binds significantly to β-secretase.
Cas No.: 1286770-55-5
Chemical Name:
Synonyms: MK8931,MK 8931,MK-8931
SMILES: C[C@]1(CS(=O)(=O)N(C(=N1)N)C)C2=C(C=CC(=C2)NC(=O)C3=NC=C(C=C3)F)F
Formula: C17H17F2N5O3S
M.Wt: 409.41
Purity: >98%
Sotrage:
Publication:
Description: MK-8931 is a BACE1 inhibitor. MK-8931 binds significantly to β-secretase.
In Vivo:
In Vitro:
References:
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC9901 Verubecestat (MK-8931) MK-8931 is a BACE1 inhibitor. MK-8931 binds significantly to β-secretase.
DC5053 LY2886721 LY2886721 is an BACE inhibitor used for the treatment of Alzheimer's Disease.
DC5180 LY2811376 LY2811376 is the first orally available non-peptidicβ-secretase(BACE1) inhibitor with IC50 of 239 nM-249 nM.
DC8400 AZD3839 AZD3839 is a potent and selective BACE1 inhibitor with Ki of 26.1 nM, about 14-fold selectivity over BACE2. Phase 1.