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(R)-Equol
DC8450  (CAS:221054-79-1)
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Fields of Application :
In contrast to the estrogen receptor (ER) selectivity of (S)-equol , (R)-equol is a weaker ER agonist that binds to ER and ER with Ki values of 27.4 and 15.4 nM, respectively.
CAS Number: 221054-79-1
Purity:

>98%

Molecular Weight: 242.3
Molecular Formula: C15H14O3
Quality Control: HPLCNMR LC/MS(Please contact us to get the QC report)
Synonyms: Isoequol
Chemical Name: 3,4-dihydro-3R-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol
Storage: 2 years -20C Powder, 2 weeks4C in DMSO,6 months-80C in DMSO
Note: Products for research use only, not for human use
Description:
Equol is a non-steroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzein by human intestinal microflora.It is a chiral molecule that exists in two enantiomeric forms.In contrast to the estrogen receptor (ER) selectivity of (S)-equol , (R)-equol is a weaker ER agonist that binds to ER and ER with Ki values of 27.4 and 15.4 nM, respectively.The (R)-enantiomer demonstrates higher ER agonist activity at ER compared to ER (EC50 = 66 and 330 nM, respectively). For the detailed information of (R)-Equol, the solubility of (R)-Equol in water, the solubility of (R)-Equol in DMSO, the solubility of (R)-Equol in PBS buffer, the animal experiment (test) of (R)-Equol, the cell expriment (test) of (R)-Equol, the in vivo, in vitro and clinical trial test of (R)-Equol, the EC50, IC50,and affinity,of (R)-Equol, For the detailed information of (R)-Equol, the solubility of (R)-Equol in water, the solubility of (R)-Equol in DMSO, the solubility of (R)-Equol in PBS buffer, the animal experiment (test) of (R)-Equol, the cell expriment (test) of (R)-Equol, the in vivo, in vitro and clinical trial test of (R)-Equol, the EC50, IC50,and affinity,of (R)-Equol, Please contact DC Chemicals.
References:
OC1=CC2=C(C=C1)C[C@H](C3=CC=C(O)C=C3)CO2
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