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calpeptin
DC7967  (CAS:117591-20-5)
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Fields of Application :
calpeptin is Ca2+-dependent protease,calpain inhibitor
CAS Number: 117591-20-5
Purity:

>98%

Molecular Weight:
Molecular Formula:
Quality Control: HPLCNMR LC/MS(Please contact us to get the QC report)
Synonyms:
Chemical Name: benzyl N-[4-methyl-1-oxo-1-(1-oxohexan-2-ylamino)pentan-2-yl]carbamate
Storage: 2 years -20C Powder, 2 weeks4C in DMSO,6 months-80C in DMSO
Note: Products for research use only, not for human use
Description:
Calpeptin is a cell permeable calpain inhibitor. Research shows that Calpeptin is an effective inhibitor of calpain 2 and can fully block cleavage of PLC- 3 enzymes. Additionally, Calpeptin has demonstrated the ability to inhibit the activities of cathepsin L and calpain-1. In muscle cell studies Calpeptin blocked the expression of aspartyl protease cathepsin D, amyloid precursor protein, and calparin. Pulmonary fibrosis research in mice have reported that Calpeptin can decrease expression of TGF-1, IL-6, collage type I1, and angiopoietin-1 mRNA. Calpeptin is an inhibitor of Calpain 1, cathepsin K, cathepsin L and PTP. Calpeptin is an activator of Rock. For the detailed information of calpeptin, the solubility of calpeptin in water, the solubility of calpeptin in DMSO, the solubility of calpeptin in PBS buffer, the animal experiment (test) of calpeptin, the cell expriment (test) of calpeptin, the in vivo, in vitro and clinical trial test of calpeptin, the EC50, IC50,and affinity,of calpeptin, Please contact DC Chemicals.
References:
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