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CaCC(inh)-A01
DC10736  (CAS:407587-33-1)
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Fields of Application :
CaCC(inh)-A01 is a non-selective inhibitor of calcium-activated chloride channels (CaCCs) that blocks ATP-stimulated chloride conductance in human salivary gland, intestinal, and bronchial epithelium (mean IC50 = 10 M).
CAS Number: 407587-33-1
Purity:

>98%

Molecular Weight: 347.4
Molecular Formula: C18H21NO4S
Quality Control: HPLCNMR LC/MS(Please contact us to get the QC report)
Synonyms: TMEM16 Blocker I
Chemical Name:
Storage: 2 years -20C Powder, 2 weeks4C in DMSO,6 months-80C in DMSO
Note: Products for research use only, not for human use
Description:
CaCC(inh)-A01 (30 M) induces full vasorelaxation of preconstricted mouse isolated mesenteric arteries in the presence or absence of chloride.CaCC(inh)-A01 also attenuates CaCC TMEM16-A-induced proliferation in cancer cell lines through targeted degradation of the protein and reduces BKCa channel activity in human red blood cells.
References:
CC(C)(C)C1CCC(C(C(O)=O)=C(NC(C2=CC=CO2)=O)S3)=C3C1
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