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iCRT 14
DC9639  (CAS:677331-12-3)
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Fields of Application :
iCRT 14 is a novel potent inhibitor of -catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity).
CAS Number: 677331-12-3
Purity:

>98%

Molecular Weight: 375.4436
Molecular Formula: C21H17N3O2S
Quality Control: HPLCNMR LC/MS(Please contact us to get the QC report)
Synonyms: iCRT14;iCRT-14
Chemical Name:
Storage: 2 years -20C Powder, 2 weeks4C in DMSO,6 months-80C in DMSO
Note: Products for research use only, not for human use
Description:
iCRT 14 is a novel potent inhibitor of -catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity). Thought to directly influence the interaction between -catenin and TCF4. Induces marked G0/G1 cell cycle arrest in HCT-116 and HT29 cell lines.
References:
O=C(S/1)N(C2=CC=CC=C2)C(C1=CC3=C(C)N(C(C)=C3)C4=CN=CC=C4)=O
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