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wiki4
DC7533  (CAS:838818-26-1)
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Fields of Application :
WIKI4 is a novel Tankyrase inhibitor with IC50 of 15 nM for TNKS2, and leads to inhibition of Wnt/beta-catenin signaling.
CAS Number: 838818-26-1
Purity:

>98%

Molecular Weight: 521.59
Molecular Formula: C29H23N5O3S
Quality Control: HPLCNMR LC/MS(Please contact us to get the QC report)
Synonyms: wiki 4
Chemical Name: 2-[3-[[4-(4-Methoxyphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]propyl]-1H-benz[de]isoquinoline-1,3(2H)-dione
Storage: 2 years -20C Powder, 2 weeks4C in DMSO,6 months-80C in DMSO
Note: Products for research use only, not for human use
Description:
Inhibitor of Wnt/-catenin signaling (EC50 ~ 75 nM). Inhibits auto-ADP-ribosylation of tankyrase 2 (TNKS2) (IC50 ~15 nM); prevents the ubiquitination and degradation of axin.For the detailed information of wiki4, the solubility of wiki4 in water, the solubility of wiki4 in DMSO, the solubility of wiki4 in PBS buffer, the animal experiment (test) of wiki4, the cell expriment (test) of wiki4, the in vivo, in vitro and clinical trial test of wiki4, the EC50, IC50,and Affinity of wiki4, Please contact DC Chemicals.
References:
C(=O)1C2=C3C(C=CC=C3C(=O)N1CCCSC1N(C3=CC=C(OC)C=C3)C(C3C=CN=CC=3)=NN=1)=CC=C2
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