Home > Inhibitors & Agonists > GPCR > Chemokine Receptor (CCR and CXCR)
Cat. No. Product name CAS No.
DC11982 CX815

A novel potent, selective CXCR2 inhibitor with IC50 of 0.4 nM.

109628-27-5
DC11981 CX4152

A novel potent, selective CXCR2 inhibitor with IC50 of 7.6 nM.

333351-27-2
DC11743 BMS-681

A potent and orally bioavailable dual antagonist of CCR2 and CCR5 with binding IC50 of 0.7 nM and 2.4 nM, respectively.

847998-92-9
DC11699 VUF11403

A potent CXCR7 (ACKR3) agonist..

1378524-61-8
DC11976 SX-576

A potent, equipotent CXCR1 and CXCR2 antagonist with IC50 of 31 nM and 21 nM, respectively.

1240494-14-7
DC11979 SB 332235

A potent, selective and competitive CXCR2 inhibitor that selectively inhibits CXCR2-mediated recruitment of β-arrestin-2 with pKi of 8.92.

276702-15-9
DC11700 Chalcone 4 hydrate

A potent, selective inhibitor of CXCL12 binding to CXCR4 and CXCR7 with IC50 of 200 nM.

1202866-96-3
DC11745 BMS-22

A potent, selective, allosteric CCR2 antagonist with binding IC50 of 5.1 nM.

445479-97-0
DC11744 CCR2-RA-[R]

A potent, selective, allosteric CCR2 antagonist with IC50 of 103 nM..

512177-83-2
DC11746 JNJ-27141491

A potent, selective, noncompetitive, orally active CCR2 antagonist with IC50 of 172 nM.

871313-59-6
DC11978 SB 265610

A potent, selective, reversible CXCR2 antagonist with with Kd of 3.48 nM.

211096-49-0
DC11983 CX797

A potent, specfic CXCR2 antagonist that inhibits IL8 down-regulation of forskolin-induced cAMP with IC50 of 7.79 uM.

1611496-70-8
DC11977 SX-517

A potent, specific, noncompetitive dual CXCR1 and CXCR2 antagonist with IC50 of 38 nM (vs. CXCL1) and 36 nM (vs. CXCL8), respectively.

1240494-13-6
DC11698 α-NETA

A small molecule CMKLR1 antagonist that inhibits chemerin-stimulated β-arrestin2 association with CMKLR1 (EC50=9.7 nM).

31059-54-8
DC11686 (R)-CCX-777

A small-molecule partial agonist of CXCR7 (ACKR3)..

1257861-18-9
DC11687 (S)-CCX-777

A small-molecule partial agonist of CXCR7 (ACKR3)..

1257861-17-8
DC11685 CCX-777

A small-molecule partial agonist of CXCR7 (ACKR3)..

1226686-36-7
DC5056 AMD3465

AMD3465 is a Potent, selective CXCR4 antagonist; exhibits 8-fold higher affinity than AMD 3100 (Cat.No. 3299). Inhibits SDF-1α-ligand binding (Ki = 41.7 nM).

185991-07-5
DC9878 ATI-2341

ATI-2341, pepducin targeting the C-X-C chemokine receptor type 4 (CXCR4), is an allosteric agonist activating the inhibitory heterotrimeric G protein (Gi) to promote inhibition of cAMP production and induce calcium mobilization.

1337878-62-2
DC11147 AZ084

AZ084 (AZ-084) is a potent, selective, allosteric, orally available CCR8 antagonist with Ki of 0.9 nM.

929300-19-6
DC11975 AZ 10397767

AZ10397767 is a potent, selective CXCR2 inhibitor that inhibits CXCL8 binding to CXCR2 with pIC50 of 9.0.

333742-63-5
DC10724 AZD2098

AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor, used for asthma research.

566203-88-1
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