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Cat. No. Product name CAS No.
DC8476 ACY-738

ACY-738 demonstrates inhibitory activity against recombinant HDAC6 with IC50 values of 1.7 nM, with respective average selectivity over class I HDACs being 100-fold.

1375465-91-0
DC3171 Agomelatine

Agomelatine is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor.

138112-76-2
DC9765 CERC-501(LY-2456302,Aticaprant)

CERC-501(LY-2456302) is a potent, selective antagonist of the kappa opioid receptor (KOR) (Ki = 0.81 nM vs. 24.0 nM and 155 nM for the μ-opioid receptor (MOR) and δ-opioid receptor (DOR), respectively.

1174130-61-0
DC12493 HT-2157(SNAP37889)

HT-2157 (SNAP 37889) is a selective, high-affinity, competitive antagonists of galanin-3 receptor (Gal3).

303149-14-6
DC12271 JNJ-54175446

JNJ-54175446 is a potent and selective brain penetrant P2X7 receptor antagonist, with pIC50s of 8.46 and 8.81 for hP2X7 receptor and rP2X7 receptor, respectively.

1627902-21-9
DC11469 APD125(Nelotanserin)

Nelotanserin is a potent 5-HT2A inverse agonist, a moderately potent 5-HT2C partial inverse agonist and a weak 5-HT2B inverse agonist, with IC50s of 1.7, 79, 791 nM in IP accumulation assays, respectively.

839713-36-9
DC10394 Org-26576

Org 26576 is a AMPA receptor positive allosteric modulator.

1026791-61-6
DC9098 Paroxetine HCl

Paroxetine hydrochloride hemihydrate is a antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs).

110429-35-1
DC9513 Radafaxine (hydrochloride)

Radafaxine Hcl(BW-306U; GW-353162A) is a potent metabolite of bupropion; selective for inhibiting the reuptake of norepinephrine over dopamine; DAT (dopamine transporter) and NET(norepinephrine transporter) transporters inhibitor, and nAChR family modulat

106083-71-0
DC8175 Rapastinel(GLYX-13)

Rapastinel(GLYX-13) is a NMDA receptor partial agonist that acts at the glycine site.

117928-94-6
DC9320 Setiptiline (maleate)

Setiptiline is a serotonin receptor antagonist.

85650-57-3
DC9319 Setiptiline

Setiptiline(Org-8282) is a serotonin receptor antagonist.

57262-94-9
DC8824 Traxoprodil

Traxoprodil is an NMDA ε 2 (NR2B) antagonist that has been studied as an alternative to serotonin selective reuptake inhibitors.

134234-12-1
DC10803 Zuranolone(SAGE-217)

SAGE-217 is a potent GABAA receptor agonist with EC50s of 296 and 163 nM for α1β2γ2 and α4β3δ GABAA receptors, respectively.

1632051-40-1
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