Home > Inhibitors & Agonists > Nuclear Receptor/Transcription Factor > Eukaryotic Initiation Factor (eIF)
Cat. No. Product name CAS No.
DC10415 4E2RCat Featured

4E2RCat is an inhibitor of eIF4E-eIF4G interaction with an IC50 of 13.5 μM.

432499-63-3
DC7349 4EGI-1 Featured

4EGI-1 is a competitive eIF4E/eIF4G interaction inhibitor by binding to eIF4E with KD of 25 μM.

315706-13-9
DC11621 eIF4A3-IN-1q

A potent, subtype-selective, orally available eIF4A3 inhibitor with IC50 of 0.14 uM.

2132392-89-1
DC12317 A-484954

A-484954 is a highly selective eukaryotic elongationfactor-2 (eEF2) inhibitor, with an IC50 of 280 nM.

142557-61-7
DC11462 NH-125 Featured

NH125 is an imidazole that has potent antibacterial properties in drug-resistant bacteria.

278603-08-0
DC28588 CMLD012612

CMLD012612 is an amidino-rocaglate containing a hydroxamate group and is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. CMLD012612 inhibits cell translation and is cytotoxic to NIH/3T3 cells with an IC50 value of 2 nM. CMLD012612 inhibits eukaryotic translation initiation by modifying the behavior of the RNA helicase (eIF4A) and possesses potent anti-neoplastic activity.

2368900-35-8
DC28589 CMLD012072

CMLD012072 is an amidino-rocaglates and is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. CMLD012072 can induce RNA clamping of eIF4A1 and eIF4A2 and possess potent anti-neoplastic activity.

2368900-33-6
DC28590 CMLD012073

CMLD012073 is an amidino-rocaglates and is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. CMLD012073 against NIH/3T3 cells with an IC50 of 10 nM. CMLD012073 inhibits eukaryotic translation initiation by modifying the behavior of the RNA helicase (eIF4A).

2368900-32-5
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