Home > Inhibitors & Agonists > GPCR > Free Fatty Acid Receptor (FFAR)
Cat. No. Product name CAS No.
DC11994 ZQ-16

A novel potent and selective agonist of GPR84 that induces calcium response with EC50 of 0.213 uM.

376616-73-8
DC11697 AM-1638

A potent, orally bioavailable, full agonist of GPR40/FFA1 with EC50 of 0.16 uM.

1142214-62-7
DC11683 LY2881835

A potent, selective, orally available GPR40 agonist with EC50 of 8 nM.

1292290-38-0
DC11682 LY2922083

A potent, selective, orally available GPR40 agonist with EC50 of 9 nM.

1309435-78-6
DC11680 LY3104607

A potent, selective, orally available GPR40 agonist with Ki of 15 nM, β-arrestin EC50 of 108 nM.

1795232-22-2
DC11623 GPR120 agonist 4x

A potent, selective, orally bioavailable GPR120 agonist with EC50 of 42 nM in calcium flux assays.

1628448-77-0
DC7867 AMG-837

AMG 837 is a potent GPR40 agonist(EC50=13 nM) with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents.

865231-46-5
DC10554 DC260126

DC260126, a small-molecule antagonist of GPR40.

346692-04-4
DC8593 GPR120 Compound A

GPR120 compound A is an orally available, high-affinity agonist of GPR120 (EC50 = ~0.35 µm) that demonstrates potent selectivity over another lipid-sensing G-protein, GPR40 (FFAR1).

1599477-75-4
DC11143 GPR40 AgoPAM AP5

GPR40 AgoPAM AP5 is a potent, selective GPR40 AgoPAM (full agonist with positive allosteric modulation) with hIP1 EC50 of 0.8 nM, high selectivity over the GPR120 receptor (EC50>30 uM).

1623194-37-5
DC8577 FFA4 (GPR120) agonist GSK137647A

GSK-137647 is a potent and selective FFA4 (GPR120) agonist (pEC50 values are 6.3, 6.2 and 6.1 at the human, mouse and rat receptor, respectively). Exhibits ≥100-fold selectivity against a panel of 61 targets including FFA1, FFA2 and FFA3.

349085-82-1
DC9458 GW-1100

GW 1100 is a selective antagonist of GPR40-mediated Ca2+ elevations in HEK293 cells stimulated by GW 9508 (an agonist of both GPR40 and GPR120, another GPCR activated by long chain fatty acids) or linoleic acid with a pIC50 value equal to 5.99.

306974-70-9
DC11681 LY2922470

LY2922470 (LY-2922470) is a potent, selective, orally available GPR40 agonist with EC50 of 7 nM.

1423018-12-5
DC11100 PBI-4050 sodium

PBI-4050 (Setogepram, PBI4050) is a synthetic analog of a medium-chain fatty acid that displays agonist and antagonist ligand affinity toward GPR40 and GPR84, respectively.

1254472-97-3
DC11099 PBI-4050

PBI-4050 (Setogepram, PBI4050) is a synthetic analog of a medium-chain fatty acid that displays agonist and antagonist ligand affinity toward GPR40 and GPR84, respectively.

1002101-19-0
DC5073 TAK-875(Fasiglifam)

TAK-875 is a potent, selective and orally bioavailable GPR40 agonist with EC50 of 0.072 μM.

1000413-72-8
DC9981 TUG891

TUG-891 is a potent and selective agonist of GPR120 with pEC50 values of 7.36 and 7.77 for human and mouse GPR120, respectively.

1374516-07-0
Page 1 / Total 1 FirstPrevNextLastGoto