Home > Inhibitors & Agonists > GPCR > GPR183 (EBI2)
Cat. No. Product name CAS No.
DC10391 EBI2 inhibitor GS682753A

GSK682753A is a selective and highly potent inverse agonist of the epstein-barr virus-induced receptor 2 (EBI2) with an IC50 of 53.6 nM.

1334294-76-6
DC8836 NIBR189 Featured

NIBR 189 is a potent and selective EBI2 (GPR183) receptor antagonist (IC50 values are 11 and 15 nM for human and mouse EBI2 receptors respectively).

1599432-08-2
DC28320 7α,25-Dihydroxycholesterol

7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol is highly potent at activating EBI2 (EC50=140 pM; Kd=450 pM). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells.

64907-22-8
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