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Cat. No. Product name CAS No.
DC9998 1400W dihydrochloride Featured

1400W dihydrochloride is a slow, tight binding, potent and highly selective inhibitor of inducible nitric oxide synthase (Kd = 7 nM).

214358-33-5
DC12367 2'3'-cGAMP Featured

2'3'-cGAMP has been used to identify small compounds capable of binding human stimulator of interferon genes (STING). It is also used to study type I interferon response to cytosolic DNA.

1441190-66-4
DC11060 3-Bromo-7-Nitroindazole

3-Bromo-7-Nitroindazole is a more potent inhibitor of nNOS than 7-nitroindazole in vitro, is also potent against iNOS, inhibits rat nNOS, bovine eNOS, and rat iNOS with IC50 of 0.17, 0.86, and 0.29 uM..

74209-34-0
DC11801 AX-000

A hit compound that inhibits the proliferation of human peripheral blood T cells stimulated with anti-CD3 with IC50 of <10 nM, inhibits TCR-Nck interaction..

340014-88-2
DC11497 IRAK4-IN-28

A novel potent, selective IRAK4 inhibitor with IC50 of 51 nM.

2196204-23-4
DC11826 ASP-6537

A novel potent, selective, reversible cyclooxygenase-1 (COX-1) inhibitor with IC50 of 4.9 nM.

524699-72-7
DC11641 Cridanimod Featured

A potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.

38609-97-1
DC11688 Avacopan Featured

Avacopan is a potent, selective, orally availale C5aR (CD88) inhibitor with IC50 of 0.1 nM.

1346623-17-3
DC5027 ABC294640(Opaganib) Featured

ABC294640 is an orally available, aryladamantane compound and selective inhibitor of sphingosine kinase-2 (SK2) with potential antineoplastic activity.

915385-81-8
DC9900 Acetaminophen

Acetaminophen is a COX inhibitor for COX-1 and COX-2 with IC50 of 113.7 μM and 25.8 μM, respectively.

103-90-2
DC9406 Ampiroxicam

Ampiroxicam(CP65703) is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.

99464-64-9
DC11802 AX-024 free base

AX-024 is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.

1370544-73-2
DC10545 AX-024 HCl Featured

AX-024 is the first-in-class inhibitor of T cell receptor (TCR); AX-024 is an orally available inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation (IC50 value 1 nM).

1704801-24-0
DC11058 BYK191023

BYK191023 (BYK-191023) is a potent, highly selective inhibitor of inducible nitric-oxide synthase (iNOS) with IC50 of 86 nM, >20-fold selectivity over nNOS and eNOS (IC50=17 and 162 uM).

608880-48-4
DC11059 BYK191023 dihydrochloride

BYK191023 dihydrochloride (BYK-191023) is a potent, highly selective inhibitor of inducible nitric-oxide synthase (iNOS) with IC50 of 86 nM, >20-fold selectivity over nNOS and eNOS (IC50=17 and 162 uM).

1216722-25-6
DC10276 C29 Featured

C29 is a potential TLR2 inhibitor.

363600-92-4
DC10330 PD-1-IN-17 Featured

PD-1-IN-17 has CAS#CAS:1673560-66-1, which is a programmed cell death-1 (PD-1) inhibitor. PD-1-IN-17 was first reported in patent WO2015033301A1, (Compound 4), inhibits 92% splenocyte proliferation at 100 nM. PD-1-IN-17 may be related to CA-170 (AUPM170), which is a potent PD-1 inhibitor and curreently under clinical trials.

1673560-66-1
DC10648 CA-4948 Featured

CA-4948 is an oral IL-1 receptor-associated kinase 4 (IRAK4) inhibitor.

1801343-74-7
DCAPI1491 Celecoxib

Celecoxib is a selective Cox-2 inhibitor (IC50 of 40 nM). Celecoxib shows low sensitivity against Cox-1 (IC50 of 15 μM). Celecoxib shows an anti-proliferative effect on nasopharyngeal carcinoma (NPC) cell lines including HNE1 (IC50of 32.86 μM) and CNE1-LM

169590-42-5
DC9169 Chloroquine diphosphate

Chloroquine diphosphate is an antimalarial drug and autophagy/lysosome inhibitor; inhibits Toll-like receptor (TLR) signalling in plasmacytoid dendritic cells (pDCs).

50-63-5
DC11642 Cridanimod sodium Featured

Cridanimod sodium is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.

58880-43-6
DC10771 CU-CPT-8m Featured

CU-CPT-8m is a nolve TLR8 inhibitor.

125079-83-6
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