Home > Research Areas > Infection
Cat. No. Product name CAS No.
DC11531 Teslexivir

A first-in-class, small molecule protein-protein inhibitor of the interaction between the E1 and E2 proteins of HPV types 6 and 11.

DC12012 PD 404182

A heterocyclic iminobenzothiazine derivative with antimicrobial and anti-inflammatory properties, a potent inhibitor of human DDAH1 activity (IC50=9 uM) and elevates cellular ADMA levels.

DC11823 BMS-929075

A highly potent, selective, orally bioavailable HCV NS5B polymerase inhibitor with IC50 of 9, 4, and 18 nM for GT1a, GT1b, and GT1b-C316N mutant in HCV replicon assay, respectively.

DC11811 SCY-078

A novel orally bioavailable fungal beta-1,3-D glucan synthetase inhibitor against Candida species C. glabrata (MIC 0.03 to 0.25 ug/ml), C. parapsilosis (MIC 0.06 to 0.25 ug/ml).

DC11854 IDX899

A novel potent, selective HIV non-nucleoside reverse transcriptase inhibitor (NNRTI) with EC50 of 1, 1.3, 2.8 and 11 nM for WT, K103N, Y181C and K103N/Y181C, respectively.

DC11825 MK-8876

A novel, broadly acting non-nucleoside inhibitor of HCV NS5B polymerase with IC50 of 3 nM and 2 nM for GT1b and GT2a, respectively.

DC11772 AZD-4316

A potent respiratory syncytial virus (RSV) fusion inhibitor..

DC11647 JNJ-2408068

A potent RSV fusion inhibitor with EC50 of 0.16 nM against some lab strains.

DC24010 Plpro-IN-6 Featured

A potent, noncovalent SARS-CoV papain-like protease (PLpro) inhibitor with IC50 of 2.6 uM.

DC11731 Ruzasvir

A potent, pan-genotype HCV NS5A inhibitor with replicon EC90 of 0.003, 0.016, 0.067, 0.036, 0.007, and 0.007 nM for GT1a, GT1a L31V, GT1a Y93H, GT2b, GT3a, and Gt4a, respectively..

DC11849 DSM421

A potent, selective P. falciparum dihydroorotate dehydrogenase (PfDHODH) with IC50 of 53 nM.

DC10797 AB423 Featured

AB-423 is the first-generation Hepatitis B Virus Capsid Assembly inhibitor, which was generally safe and well tolerated in Phase 1 healthy volunteer studies.

DC9029 Abacavir

Abacavir is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS.

DCAPI1273 Acyclovir (Aciclovir)

Acyclovir (Aciclovir)

DC10513 AFN-1252(Debio 1452) Featured

AFN-1252(Debio 1452) is a potent inhibitor of enoyl-acyl carrier protein reductase (FabI), inhibited all clinical isolates of Staphylococcus aureus and Staphylococcus epidermidis at concentrations of ≤0.12 μg/ml.

DC10621 Amenamevir Featured

Amenamevir, also known as ASP2151, is a herpes virus helicase-primase inhibitor.

DC7058 Amprenavir

Amprenavir (Agenerase) is a HIV protease inhibitor(Ki=0.6 nM) used to treat HIV infection.

DC11738 SCYX-7158

An orally-active, CNS permeable benzoxaborole antiprotozoal agent.

DC9827 AN3365(Epetraborole) Featured

AN3365 is a first-in-class antibiotic that demonstrates potent activity across a wide spectrum of Gram-negative bacteria, including those resistant to many other antibiotics.

DCAPI1051 Arbidol HCl (Umifenovir) Featured

Umifenovir is currently being investigated as a potential treatment and prophylactic agent for COVID-19 caused by SARS-CoV2 infections in combination with both currently available and investigational HIV therapies. Arbidol hydrochloride (Umifenovir hydrochloride) is an broad-spectrum antiviral chemical agent which can inhibit cell entry of enveloped viruses by blocking viral fusion with host cell membrane IC50 value: Target: Antiviral; Anti-influenza agent in vitro: Arbidol was found to present potent inhibitory activity against enveloped and non-enveloped RNA viruses, including FLU-A, RSV, HRV 14 and CVB3 when added before, during, or after viral infection, with 50% inhibitory concentration (IC50) ranging from 2.7 to 13.8 microg/ml.

DC3150 Atazanavir Featured

Atazanavir is a HIV protease inhibitor with Ki of 2.66 nM.

DC9480 Atazanavir (sulfate)

Atazanavir sulfate is a sulfate salt form of atazanavir that is an highly potent HIV-1 protease inhibitor.

Page 1 / Total 8 FirstPrevNextLastGoto