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Cat. No. Product name CAS No.
DC11497 IRAK4-IN-28

A novel potent, selective IRAK4 inhibitor with IC50 of 51 nM.

2196204-23-4
DC10648 CA-4948 Featured

CA-4948 is an oral IL-1 receptor-associated kinase 4 (IRAK4) inhibitor.

1801343-74-7
DC8328 IRAK-1/4 Inhibitor Featured

Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor is a benzimidazole compound that acts as a cell-permeable, potent selective inhibitor of IL-1 kinases.

509093-47-4
DC9491 IRAK inhibitor 1 Featured

IRAK inhibitor 1 is an interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitor.

1042224-63-4
DC9492 IRAK inhibitor 2

IRAK inhibitor 2 is interleukin-1 receptor associated kinase inhibitor .

928333-30-6
DC10584 IRAK4-IN-1 Featured

IRAK4-IN-1 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor with an IC50 of 7 nM.

1820787-94-7
DC11185 PF-06426779

PF-06426779 (PF06426779) is a potent, selective IRAK4 inhibitor with IC50 of 1 nM against full-length IRAK4 kinase and cell-based IC50 of 12 nM.

1817628-40-2
DC28331 IRAK4-IN-4

IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor extracted from patent CN107163044A, Compound15, has an IC50 of 2.8 nM. IRAK4-IN-4 also inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.

1850276-58-2
DC31041 BMS-986126

BMS-986126 is a potent, highly selective inhibitor of IRAK4 kinase with IC50 of 5.3 nM, displays >100-fold selective for IRAK4 over a panel of 214 kinases.

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