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Cat. No. Product name CAS No.
DC7675 BX-471(ZK 811752)

BX471 is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1); exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.

217645-70-0
DC10357 Cenerimod

Cenerimod (ACT-334441) is a potent and orally available sphingosine 1-phosphate 1 receptor (S1P1) agonist extracted from patent WO 2016184939 A1 and WO 2011007324 A1, example 1, with an EC50 of 2.7 nM.

1262414-04-9
DC8936 Fingolimod

Fingolimod(FTY720 free base) is a S1P antagonist with IC50 of 0.033 nM.

162359-55-9
DC3154 Fingolimod HCl(FTY-720)

FTY720 (Fingolimod, Gilenya) is a S1P antagonist with IC50 of 0.033 nM.

162359-56-0
DC2071 ABR-215062 (Laquinimod)

Laquinimod (ABR-215062) is a potent immunomodulator.

248281-84-7
DC3167 MK0812

MK-0812 is chemokine receptor CCR-2 antagonist

624733-88-6
DC8281 Ozanimod (RPC1063)

Ozanimod (RPC1063) is a selective S1P1R modulator

1306760-87-1
DC8741 Plerixafor octahydrochloride

Plerixafor octahydrochloride(AMD3100 8HCL) is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively.

155148-31-5
DC9742 Ponesimod

Ponesimod(ACT-128800) is an orally active, selective sphingosine-1-phosphate receptor 1 (S1P1) immunomodulator with EC50 of 5.7 nM.

854107-55-4
DC9490 Zaurategrast

Zaurategrast(CDP-323) is an oral α4-integrin inhibitor.

455264-31-0
DC12355 Ceralifimod (ONO-4641)

Ceralifimod is selective, high potent agonist for sphingosine 1-phosphate receptors 1 and 5, with EC50s of 27.3, 334 pM for human S1P receptor 1 and 5, respectively.

891859-12-4
DC7694 BAF312 (Siponimod)

BAF312 is a potent and selective agonist of S1P with EC50 value of 0.39nM for S1P1 receptors and 0.98nM for S1P5 receptors, respectively

1230487-00-9
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