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Cat. No. Product name CAS No.
DC9867 prostaglandin D2(PGD2) inhibitor

A small molecule compound of prostaglandin D2(PGD2) inhibitor.

885066-67-1
DC12213 AGN 210676 (Simenepag)

AGN 210676 is a selective prostaglandin EP2 agonist extracted from patent US20070203222A1, Compound example 23, has an EC50 of 5 nM.

910562-15-1
DC12230 AM211

AM211 is a potent, selective and orally bioavailable prostaglandin D2 (PGD2) receptor type 2 (DP2) antagonist

1175526-27-8
DC6310 AMG 853(AMG853;Vidupiprant)

AMG 853 is novel a CRTH2 and DP Dual Antagonist.

1169483-24-2
DC11174 ASP7657

ASP7657 (ASP-7657) is a potent, selective, orally active prostaglandin EP4 receptor antagonist with Ki values of 6.02 nM and 2.21 nM for rat and human EP4 receptors, resepctively.

1196045-28-9
DC7364 AT-56

AT-56 is a selective, competitive, and highly bioavailable inhibitor of lipocalin-type prostaglandin D synthase (L-PGDS) with a Ki value of 75 µM.

162640-98-4
DC7572 AZD1981

AZD1981 is a potent, selective CRTh2 (DP2) receptor antagonist with IC50 of 4 nM, showing >1000-fold selectivity over more than 340 other enzymes and receptors, including DP1

802904-66-1
DCAPI1079 Bimatoprost

Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.

155206-00-1
DC10847 CAY10441(RO1138452)

CAY10441 is a Selective prostacyclin IP receptor antagonist.

221529-58-4
DC12099 CAY10595

CAY10595 is a potent CRTH2/DP2 receptor antagonist that binds to the human receptor with a Ki of 10 nM.

916047-16-0
DCAPI1545 Cloprostenol sodium

Cloprostenol Sodium is a synthetic F series prostaglandin that functions as a potent agonist towards the PGF2αR (FP receptor). It is known that Cloprostenol Sodium is less selective than other agonists such as fluprostenol, however it displays more potenc

55028-72-3
DC9303 Taprenepag(CP-544326)

CP-544326 is a selective prostaglandin EP(2) agonist on intraocular pressure in preclinical models of glaucoma.

752187-80-7
DC11154 CR6086

CR6086 (CR-6086) is a potent, selective prostaglandin E2 receptor 4 (EP4) antagonist with Ki of 16.6 nM (hEP4 receptor), inhibits PGE2-stimulated cAMP production with IC50 of 22 nM.

DC9863 Dinoprost

Dinoprost(Prostaglandin F2α) is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.

551-11-1
DC10563 E-7046

E7046 is an orally bioavailable and specific EP4 antagonist, with IC50 of 13.5 nM and Ki of 23.14 nM, exhibiting anti-tumor activities.

1369489-71-3
DC9016 Etamsylate

Ethamsylate is a haemostatic drug, also inhibits biosynthesis and action of those prostaglandins.

2624-44-4
DC9685 Evatanepag (CP-533536)

Evatanepag (CP-533536) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.

223488-57-1
DC11278 Fevipiprant

Fevipiprant(QAW039) is a selective, potent, reversible competitive CRTh2 antagonist with an in vitro dissociation constant KD value of 1.1nM at the CRTh2 receptor and an IC50 value of 0.44 nM for inhibition of PGD2-induced eosinophil shape change.

872365-14-5
DC8266 GW-627368X

GW 627368X is a selective prostanoid EP4 receptor competitive antagonist with additional affinity at TP receptors (pKi values are 7.0 and 6.8 in competition radioligand bioassays).

439288-66-1
DC11377 L-826,266

L-826,266 is a potent and selective competitive antagonist of the prostaglandin E2 receptor subtype EP3 (Ki = 0.8 nM).

244101-03-9
DC8635 Latanoprost

Latanoprost is a prodrug (isopropyl ester) of 17-phenyl-13,14-dihydro prostaglandin F2α.

130209-82-4
DC8249 MF498

MF498 is a novel and selective E prostanoid receptor 4 (EP4) inhibitor, relieves joint inflammation and pain in rodent models of rheumatoid and osteoarthritis.

915191-42-3
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