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Cat. No. Product name CAS No.
DC11439 Nemorexant

ACT-541468 is a dual orexin receptor antagonist.

1505484-82-1
DC7692 Almorexant HCl (Act-078573) Featured

Almorexant(ACT078573) is a potent and competitive dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist with Ki values of 1.3 and 0.17 nM for OX1 and OX2, respectively.

913358-93-7
DC11028 EMD-281014 hydrochloride

EMD-281014 hydrochloride is a potent, highly selective 5-HT2A antagonist with Ki of 0.87 nM, displays little to no affinity for 5-HT2C receptors (Ki=557 nM), human D2 receptors and IKr channels.

443144-27-2
DC11027 EMD-281014

EMD-281014 is a potent, highly selective 5-HT2A antagonist with Ki of 0.87 nM, displays little to no affinity for 5-HT2C receptors (Ki=557 nM), human D2 receptors and IKr channels.

443144-26-1
DC11090 GR3027 Featured

GR3027 (Golexanolone) is a GABA-A receptor modulating steroid antagonist that selectively antagonizes the enhanced activation of GABAA receptors by neurosteroids such as allopregnanolone and THDOC.

2089238-18-4
DC4137 Indiplon Featured

Indiplon is a novel sedative-hypnotic recently approved for the treatment of insomnia.

325715-02-4
DC8173 Lemborexant(E2006) Featured

Lemborexant (E-2006) is a dual antagonist of the orexin OX1 and OX2 receptors which is under development for treatment of insomnia.

1369764-02-2
DC8642 Lorediplon Featured

Lorediplon is a new GABAA modulator Drug for treatment of insomnia.

917393-39-6
DC9966 MK-1064 Featured

MK-1064 is a selective orexin 2 receptor antagonist (2-SORA) for the research of insomnia.

1207253-08-4
DC7646 MK3697

MK-3697 is a third insomnia drug, currently being developed by Merck. MK-3697 is a potent and selective Orexin receptor antagonist with Ki = 0.95 nM.

1224846-01-8
DC9465 Pitolisant (hydrochloride) Featured

Pitolisant Hcl(BF2.649;Ciproxidine ) is a novel, potent, and selective nonimidazole inverse agonist at the recombinant human H3 receptor (Ki=0.16 nM).

903576-44-3
DC11529 Solriamfetol hydrochloride Featured

Solriamfetol hydrochloride (JZP-110, R-228060, ADX-N05, YKP-10A) is a norepinephrine-dopamine reuptake inhibitor that inhibits dopamine and norepinephrine transporter with IC50 of 2.9 and 4.4 uM, respectively.

178429-62-4
DC5017 Suvorexant (MK-4305) Featured

Suvorexant (MK-4305) is a potent, selective, and orally bioavailable antagonist of OX1R and OX2R currently under clinical investigation as a novel therapy for insomnia.

1030377-33-3
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