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Cat. No. Product name CAS No.
DC10868 Cilofexor Featured

Cilofexor (GS-9674, GS9674) is novel specific, non-steroidal farnesoid X receptor (FXR) agonist that reduces liver fibrosis and ameliorates portal hypertension in rat NASH models.

1418274-28-8
DC9762 Emricasan Featured

Emricasan (IDN-6556, PF-03491390) is a potent irreversible pan-caspase inhibitor.

254750-02-2
DC10772 Lanifibranor

Lanifibranor, also known as IVA-337, is a peroxisome proliferator-activated receptors (PPAR) agonist.

927961-18-0
DC9995 MGL-3196(Resmetirom) Featured

MGL-3196 is a potent and highly selective thyroid hormone receptor β agonist in clinical trials for the treatment of dyslipidemia.

920509-32-6
DC10173 Firsocostat(ND-630,GS-0976) Featured

ND-630 is an acetyl-CoA carboxylase (ACC) inhibitor; inhibits human ACC1 and ACC2 with IC50 values of 2.1 and 6.1 nM, respectively.

1434635-54-7
DC8390 Oltipraz Featured

Oltipraz is a potent Nrf2 activator and a potent inducer of Phase II detoxification enzymes, most notably glutathione-S-transferase (GST). Phase 3.

64224-21-1
DC10737 Tropifexor (LJN452) Featured

Tropifexor (LJN452) is a highly potent non-bile Acid FXR Agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH).

1383816-29-2
DC9873 Selonsertib(GS-4997) Featured

Selonsertib(GS-4997)is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities.

1448428-04-3
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