Home > Inhibitors & Agonists > Tyrosine Kinase > TAM Receptor (Tyro3-Axl-Mer)
Cat. No. Product name CAS No.
DCD-057 n-Butylidenephthalide

>98%,Standard References

551-08-6
DC10337 CEP-40783

CEP-40783 is a potent, selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively.

1437321-24-8
DC7999 LDC1267

LDC1267 is a highly selective TAM(Tyro3, Axl and Mer) kinase inhibitor with IC50 of <5 nM/8 nM/29 nM for Tyro3,Axl and Mer respectively.

1361030-48-9
DC10995 R916562

R916562 (R562) is a potent, dual Axl/VEGF-R2 inhibitor with celluar IC50 of 136 nM for Axl.

1037798-41-6
DC11690 RU-302

RU-302 is a small molecule pan-TAM inhibitor that targets the TAM Ig1-Gas6 interface, blocks Gas6-dependent TAM activation.

1182129-77-6
DC11265 S49076 (hydrochloride) Featured

S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab.

1265966-31-1
DC10071 S49076 Featured

S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3 with IC50 values below 20 nM.

1265965-22-7
DC8535 SGI-7079 Featured

SGI-7079 is a novel Axl inhibitor.

1239875-86-5
DC8223 TP-0903 Featured

TP-0903 is a a high-affinity Axl inhibitor with IC50 of 27 nM.

1341200-45-0
DC9289 UNC-2025 HCl Featured

UNC-2025 is a potent and orally bioavailable dual MER/FLT3 inhibitor with IC50 of 0.74 nM and 0.8 nM, respectively, about 20-fold selectivity over Axl and Tyro3.

DC7931 UNC2025 Featured

UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM for Mer/Flt3.

1429881-91-3
DC10127 UNC569 Featured

UNC569 is a novel small-molecule MER inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivo.

1350547-65-7
DC11689 RU-301 Featured

RU-301 (RU301) is a small molecule pan-TAM inhibitor that targets the TAM Ig1-Gas6 interface, blocks Gas6-dependent TAM activation.

1110873-99-8
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