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COA of Gefitinib impurity 2

Description:

Gefitinib impurity 2 is the impurity of Gefitinib. Gefitinib is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity.

Chemical Information

Catalog Novel inhibitors
Purity of current batch 98%
CAS 246512-44-7
Molecular Weight (MW) 309.36082
Molecular Formula C15H23N3O4
Storage Please store the product under the recommended conditions in the Certificate of Analysis.

Handling:

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.