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COA of Compound 38 (NNMT inhibitor)

Description:

Compound 38 (NNMT inhibitor) is a potent uncompetitive inhibitors of nicotinamide n-methyltransferase (NNMT). Compound 38 inhibits NNMT in both in vitro biochemical and cell-based assays with IC50 = 42 nM and 38 nM, respectively. Compound 38 shows favorable PK/PD and safety profiles as well as excellent oral bioavailability and pharmaceutical properties.

Chemical Information

Catalog Featured products
Purity of current batch >98%
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Handling:

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.