Description:
AZD8359 is a STEAP2-targeting T-cell engager. STEAP2 is a highly specific prostate-associated surface antigen that is strongly expressed across all stages of prostate adenocarcinoma. Built on AstraZeneca’s TITAN platform, AZD8359 is engineered to bias activity toward CD8+ T cells. Its "2+1" antibody format favors CD8+ over CD4+ T cells, preserving tumor cell killing while reducing the risk of cytokine release syndrome and off-target toxicity.
Handling:
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance,
we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one
month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at
least 1 hour.