This therapeutic candidate, known as EpiTAC, is a tissue-selective bispecific antibody developed for EGFR-driven cancers. It works by binding to ITGB6 (integrin subunit beta-6), which promotes the degradation of both wild-type and mutant forms of EGFR specifically within tumor tissues. This triggers lysosome-mediated protein breakdown, potentially expanding the reach of EGFR-targeted therapy beyond currently defined mutation-restricted patient populations.

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.