Description:
PPIL4 is a member of the cyclophilin family, characterized by its peptidyl-prolyl cis–trans isomerase activity, which facilitates the folding of target proteins through accelerated rotation around proline imidic peptide bonds. In addition to this isomerase function, PPIL4 harbors an RNA-recognition motif (RRM), implicating it in post-transcriptional processes. This dual-domain architecture suggests that PPIL4 not only participates in protein conformation quality control but also interfaces with the spliceosomal machinery and broader RNA metabolic pathways, potentially coupling protein folding events with co-transcriptional or post-transcriptional regulation.
Handling:
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance,
we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one
month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at
least 1 hour.