Desferricoprogen is a hydrophobic fungal iron chelator siderophore. Desferricoprogen reduces atherosclerotic plaque formation and inhibits lipid peroxidation in aortic roots in ApoE−/− mice on an atherogenic diet. Desferricoprogen can lower the level of oxidized LDL (oxLDL) and inhibit oxLDL-induced HO-1, CD36, and TNF-α mRNA expression. Desferricoprogen inhibits TNF-α-induced endothelial cell activation, VCAM-1, ICAM-1 experssion and preserves endothelial monolayer integrity. Desferricoprogen can be used for the research of atherosclerosis.

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.