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COA of Flt3 Inhibitor 17
Description:
Novel FLT3 inhibitor, displaying potent inhibitory activity against the FLT3-ITD mutant (IC 50 = 0.8 nM) and good selectivity over c-KIT kinase (over 500-fold), selectively inhibiting the proliferation of FLT3-ITD-positive AML cell lines MV4-11 (IC 50 = 2
Chemical Information
| Catalog | Novel inhibitors |
|---|---|
| Molecular Weight (MW) | |
| Molecular Formula | |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Handling:
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.