PI3Kα-IN-27 Datasheet DC Chemicals

Description	PI3Kα-IN-27 (Compound 50b) is an orally active PI3K-α inhibitor, with an IC50 of 40 nM. PI3Kα-IN-27 effectively inhibits PAK3, p110α, phospho-mTOR and phospho-ERK1/2. PI3Kα-IN-27 induces early Apoptosis. PI3Kα-IN-27 shows anticancer activity against pancreatic cancer, lung cancer, breast cancer.
Cat.No	DC81286
Name	PI3Kα-IN-27

Chemical Properties

CAS	2093387-94-9
Formula	C13H13N3O3S
MW	291.33
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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