(1S,2S,3R)-PLX-4545 Datasheet DC Chemicals

Description	(1S,2S,3R)-PLX-4545 is the (1S,2S,3R) enantiomer of PLX-4545. PLX-4545 is an orally active and selective cereblon-based molecular glue degrader of IKZF2 (zinc finger transcription factor Helios). PLX-4545 can reprogram immunosuppressive regulatory T cells into pro-inflammatory effector T cells, thereby enhancing anti-tumor immune responses.
Cat.No	DC78948
Name	(1S,2S,3R)-PLX-4545

Chemical Properties

CAS	2892066-42-9
Formula	C28H31N3O4
MW	473.56
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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