AC 187 TFA Datasheet DC Chemicals
Description AC 187 TFA is an orally active, potent amylin receptor antagonist (IC50= 0.48 nM) that displays 38-fold and 400-fold selectivity over calcitonin and CGRP receptors respectively. AC 187 TFA blocks amyloid β-induced neurotoxicity by attenuating the activation of initiator and effector caspases in vitro. AC 187 TFA increases glucagon secretion, accelerates gastric emptying, alters plasma glucose levels and increases food intake in vivo.
Cat.No DC41827
Name AC 187 TFA

Chemical Properties

CAS
Formula C129H206F3N37O42
MW 3004.27
Storage Please store the product under the recommended conditions in the Certificate of Analysis.

References

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