ARQ171 Datasheet DC Chemicals
Description BMS-214662 is a Farnesyltransferase inhibitor , is also a nonsedating benzodiazepine derivative with potential antineoplastic activity. BMS-214662 inhibits the enzyme farnesyltransferase and the post-translational farnesylation of number of proteins involved in signal transduction, which may result in the inhibition of Ras function and apoptosis in susceptible tumor cells. This agent may reverse the malignant phenotype of H-Ras-transformed cells and has been shown to be active against tumor cells with and without Ras mutations.
Cat.No DC31343
Name ARQ171

Chemical Properties

CAS 95981-08-9
Formula C25H24CLN5O2S2
MW 526.07
Storage

References

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