Cucurbitacin IIb Datasheet DC Chemicals

Description	Cucurbitacin IIb is an active component isolated from Hemsleya amabilis, induces apoptosis with anti-inflammatory activity. Cucurbitacin IIb inhibits phosphorylation of STAT3, JNK and Erk1/2, enhances the phosphorylation of IκB and NF-κB (p65), blocks nuclear translocation of NF-κB (p65) and decreases mRNA levels of IκBα and TNF-α.
Cat.No	DCZ-123
Name	Cucurbitacin IIb

Chemical Properties

CAS	50298-90-3
Formula	C30H48O7
MW	520.702
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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