A-485 Datasheet DC Chemicals
Description A-485 is a highly potent and selective small-molecule inhibitor targeting the catalytic activity of p300/CBP histone acetyltransferases (HATs). It demonstrates remarkable inhibitory potency, with IC50 values of 9.8 nM (p300) and 2.6 nM (CBP).
Cat.No DC11511
Name A-485

Chemical Properties

CAS 1889279-16-6
Formula C25H24F4N4O5
MW 536.4755
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Lasko LM, et al. Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours. Nature. 2017 Oct 5;550(7674):128-132.
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