NEK7 degrader (Compound 17) Datasheet DC Chemicals

Description	NEK7 degrader-1 is a NEK7 molecular glue degrader with a DC50 of 9  nM. NEK7 degrader-1 dose-dependently inhibits caspase-1 activity and IL-Ιβ release in macrophages in response to NLRP3 inflammasome activation. NEK7 degrader-1 can be used for autoinflammatory and autoimmune disorders like multiple sclerosis, neurodegeneraive diseases like Alzheimer's disease and cardiovascular and melabolic disorders like pericarditis and Type 2 diabetes research.
Cat.No	DC60948
Name	NEK7 degrader (Compound 17)

Chemical Properties

CAS	3069891-91-1
Formula	C21H22CL2N4O3
MW	449.330382823944
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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