DM4-SMCC Datasheet DC Chemicals
Description ​​DM4-SMCC​​ is an ​​antibody-drug conjugate (ADC) payload​​ that combines the potent ​​antitubulin agent DM4​​ with a ​​non-cleavable SMCC linker​​. This conjugate is designed to deliver cytotoxic effects specifically to tumor cells, leveraging DM4's ability to disrupt microtubule dynamics. The stable SMCC linker ensures controlled drug release, enhancing the ADC's ​​antitumor activity​​ while minimizing off-target toxicity.
Cat.No DC67529
Name DM4-SMCC

Chemical Properties

CAS 1228105-52-9
Formula C54H72CLN5O16S
MW 1114.69139385223
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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